Rachela Popovtzer is an Associate Professor in the Faculty of Engineering and a member of the Bar-Ilan Institute of Nanotechnology and Advanced Materials (BINA), Israel. She received her B.Sc. degree in physics from BIU and her M.Sc. and PhD in Electrical Engineering from Tel Aviv University. She was a postdoctoral fellow in the University of Michigan with Prof. Raoul Kopelman. Popovtzer joined the faculty of Engineering in 2008, here she is currently the head of the Bioengineering track and the Laboratory for Nano-medicine. Rachela Popovtzer is a winner of numerous international grants and awards, such as the Intel Prize, the EU Environment and Living foundation Prize and the Atol Charitable Trust Fellow in Nano Medicine. Her current research interest focuses on the development of ’smart’ nanoprobes for theranostic applications.
One of the main limitations of the highly used cancer imaging technique, PET-CT, is its inability to distinguish between cancerous lesions and post treatment inflammatory conditions. The reason for this lack of specificity is that [F18].
FDG-PET is based on increased glucose metabolic activity, which characterizes both cancerous tissues and inflammatory cells. To overcome this limitation, we developed a novel nanoparticle-based approach, utilizing Glucose-Functionalized Gold Nanoparticles (GF-GNPs) as a metabolically targeted CT contrast agent. Our approach demonstrates specific tumor targeting and has successfully distinguished between cancer and inflammatory processes in a combined tumor-inflammation mouse model, due to dissimilarities in angiogenesis occurring under different pathologic conditions. This study provides a new set of capabilities in cancer detection, staging and follow-up, paving the way for improved specificity.
Congratulations to our lab member, Dr. Inbal Hazkany, for receiving the the Israeli Medical Association (IMA) prize for Outstanding Basic Research. The ceremony was held in the presence of the IMA chairman, the Scientific Council members and all six outstanding prizewinning researchers. Dr. Hazkany studied the impact of molecular profiling guided targeted gold nanoparticles on radiosensitivity of metastatic salivary gland adenoid cystic carcinoma.More news
Our PhD students Oshra Betzer, Tamar Dreifuss and Rinat Meir participated in the World Molecular Imaging Congress (WMIC) in New York, after all three won travel grants from the Ministry of Science and Technology for presenting their research in the conference.More news
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